Management of Pregnancy After Conization and Radical Trachelectomy

Cervical intraepithelial neoplasia (CIN) is commonly diagnosed in women of child-bearing age. (Castle et al., 2009) The excisional treatments of CIN include cold-knife conization, laser conization, loop electrosurgical excision procedure (LEEP), and large loop excision of the transformation zone (LLETZ). CIN is also treated by ablative procedures such as laser vaporization and cryotherapy. Recently, human papilloma virus (HPV) has led to the understanding of pathogenesis and management of cervical diseases. (Moscicki et al., 2004) The screening and subsequent treatment of CIN significantly reduces the risk of invasive cervical cancer, but the impact of excisional cervical treatment on subsequent pregnancy outcome must be evaluated.